Oxycodone 5 mg and codeine 30 mg are, therefore, commonly prescribed in fixed combination with 325 mg and 300 mg acetaminophen, respectively. Addition of acetaminophen to either opioid appears to improve the efficacy of both.
A single dose of 10 mg of oxycodone, a Schedule II controlled substance, is thought to be approximately 2–3 times stronger than a single dose of 60 mg of codeine, a less restricted Schedule III controlled substance. Oral opioids are frequently prescribed for short-term outpatient moderate to severe pain management following discharge from the emergency department (ED).
Pain, Oxycodone/Acetaminophen, Codeine/Acetaminophen, Emergency Department Introduction
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